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BICAN: Cell Census of Developing Brain

The new frontier in understanding human and mammalian brain development

perspective

Tomasz J. Nowakowski, Patricia R. Nano, Katherine S. Matho, Emily K. Corrigan, Wubin Ding, Yuan Gao, Matthew Heffel, Jaikishan Jayakumar, Harris S. Kaplan, Fae N. Kronman, Rothem Kovner, Camiel C.A. Mannens, Mengyi Song, Marilyn R. Steyert, Sridevi Venkatesan, Jenelle L. Wallace, Li Wang, Jonathan M. Werner, Di Zhang, Guohua Yuan, Guolong Zuo, Seth A. Ament, Carlo Colantuoni, Catherine Dulac, Rong Fan, Jesse Gillis, Arnold Kriegstein, Fenna M. Krienen, Yongsoo Kim, Sten Linnarsson, Partha Mitra, Alex Pollen, Nenad Sestan, Daniel J. Tward, Cindy T. J. van Velthoven, Zizhen Yao, Aparna Bhaduri, Hongkui Zeng

Authors

Tomasz J. Nowakowski, Patricia R. Nano, Katherine S. Matho, Emily K. Corrigan, Wubin Ding, Yuan Gao, Matthew Heffel, Jaikishan Jayakumar, Harris S. Kaplan, Fae N. Kronman, Rothem Kovner, Camiel C.A. Mannens, Mengyi Song, Marilyn R. Steyert, Sridevi Venkatesan, Jenelle L. Wallace, Li Wang, Jonathan M. Werner, Di Zhang, Guohua Yuan, Guolong Zuo, Seth A. Ament, Carlo Colantuoni, Catherine Dulac, Rong Fan, Jesse Gillis, Arnold Kriegstein, Fenna M. Krienen, Yongsoo Kim, Sten Linnarsson, Partha Mitra, Alex Pollen, Nenad Sestan, Daniel J. Tward, Cindy T. J. van Velthoven, Zizhen Yao, Aparna Bhaduri, Hongkui Zeng

Citation

Nowakowski, T., et al. The new frontier of human and mammalian brain development. Nature (2025). https://doi.org/10.1038/s41586-025-09652-1

Summary

A perspective piece covering recent advances in technologies and approaches to understanding brain atlases and how they culminate in this series of cell atlases for development.

Data and Tools

Resource Name
Resource URL
Description
https://www.nature.com/articles/d41586-025-03450-5
News and Views
Perspective
https://www.nature.com/articles/s41586-025-09652-1
Perspective article

The Brain Cell Data Center (BCDC) at the Allen Institute for Brain Science provides a foundational community resource on cell types in the mammalian brain by sharing the integrated data, tools, and knowledge produced by the BRAIN Initiative Cell Atlas Network (BICAN).

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